This course provides an introduction to biomedical engineering principles using foundational resources from molecular and cellular biology and physiology, and relating them to various subspecialties of biomedical engineering. The essential molecular biology, cellular biology, and human physiology background are included for students to understand the context in which biomedical engineers work. The course also highlights important advances made over recent years, including iPS cells, microRNA, Nano medicine, imaging technology, biosensors, and drug delivery systems, giving students a modern description of the various subfields of biomedical engineering. Further, this introductory course will provide concrete examples of applying engineering knowledge to solve problems related to human medicine as well as concrete examples of recent technological breakthroughs.